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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
PPP1R2
All Species:
18.18
Human Site:
S188
Identified Species:
44.44
UniProt:
P41236
Number Species:
9
Phosphosite Substitution
Charge Score:
0.22
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P41236
NP_006232.1
205
23015
S188
E
S
M
N
T
E
E
S
N
Q
G
S
T
P
S
Chimpanzee
Pan troglodytes
XP_516963
205
23027
S188
E
S
M
N
T
E
E
S
N
Q
G
S
T
P
S
Rhesus Macaque
Macaca mulatta
XP_001097826
205
22972
S188
E
S
M
N
T
E
E
S
N
Q
G
S
T
P
S
Dog
Lupus familis
XP_548958
208
22793
L188
A
S
E
H
S
T
G
L
E
E
S
S
D
E
V
Cat
Felis silvestris
Mouse
Mus musculus
Q9DCL8
206
23101
S189
D
S
M
N
V
E
E
S
S
Q
G
S
T
T
S
Rat
Rattus norvegicus
P50411
205
23053
S188
D
S
M
N
I
E
E
S
N
Q
G
S
T
A
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001511436
176
19998
D160
E
E
M
Q
E
A
A
D
V
E
S
M
N
T
E
Chicken
Gallus gallus
NP_001026484
237
26006
M204
D
A
P
D
V
E
T
M
N
T
E
D
I
E
H
Frog
Xenopus laevis
NP_001091136
188
21452
E172
L
A
G
E
I
D
E
E
E
D
E
D
E
E
M
Zebra Danio
Brachydanio rerio
NP_991231
204
22948
T188
E
M
K
D
D
T
E
T
E
D
I
T
V
D
P
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Honey Bee
Apis mellifera
Nematode Worm
Caenorhab. elegans
Sea Urchin
Strong. purpuratus
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
99.5
98.5
50
N.A.
83.9
84.8
N.A.
58
54.4
57.5
56
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
100
99.5
99.5
67.3
N.A.
90.2
91.2
N.A.
68.2
65.4
70.7
71.2
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
100
100
100
13.3
N.A.
73.3
73.3
N.A.
13.3
13.3
6.6
13.3
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
100
100
100
33.3
N.A.
86.6
80
N.A.
20
33.3
20
33.3
N.A.
N.A.
N.A.
N.A.
N.A.
Percent
Protein Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
N.A.
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
10
20
0
0
0
10
10
0
0
0
0
0
0
10
0
% A
% Cys:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% C
% Asp:
30
0
0
20
10
10
0
10
0
20
0
20
10
10
0
% D
% Glu:
50
10
10
10
10
60
70
10
30
20
20
0
10
30
10
% E
% Phe:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% F
% Gly:
0
0
10
0
0
0
10
0
0
0
50
0
0
0
10
% G
% His:
0
0
0
10
0
0
0
0
0
0
0
0
0
0
10
% H
% Ile:
0
0
0
0
20
0
0
0
0
0
10
0
10
0
0
% I
% Lys:
0
0
10
0
0
0
0
0
0
0
0
0
0
0
0
% K
% Leu:
10
0
0
0
0
0
0
10
0
0
0
0
0
0
0
% L
% Met:
0
10
60
0
0
0
0
10
0
0
0
10
0
0
10
% M
% Asn:
0
0
0
50
0
0
0
0
50
0
0
0
10
0
0
% N
% Pro:
0
0
10
0
0
0
0
0
0
0
0
0
0
30
10
% P
% Gln:
0
0
0
10
0
0
0
0
0
50
0
0
0
0
0
% Q
% Arg:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% R
% Ser:
0
60
0
0
10
0
0
50
10
0
20
60
0
0
40
% S
% Thr:
0
0
0
0
30
20
10
10
0
10
0
10
50
20
0
% T
% Val:
0
0
0
0
20
0
0
0
10
0
0
0
10
0
10
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% W
% Tyr:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _